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Dernières publications
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Dylan Moutachi, Janek Hyzewicz, Pauline Roy, Mégane Lemaitre, Damien Bachasson, et al.. Treadmill running and mechanical overloading improved the strength of the plantaris muscle in the dystrophin‐desmin double knockout (DKO) mouse. The Journal of Physiology, In press, ⟨10.1113/JP286425⟩. ⟨hal-04643936⟩
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Medhi Hassani, Dylan Moutachi, Mégane Lemaitre, Alexis Boulinguiez, Denis Furling, et al.. Beneficial effects of resistance training on both mild and severe mouse dystrophic muscle function as a preclinical option for Duchenne muscular dystrophy. PLoS ONE, 2024, 19, ⟨10.1371/journal.pone.0295700⟩. ⟨hal-04501283⟩
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Antonio Atalaia, Dagmar Wandrei, Nawel Lalout, Rachel Thompson, Adrian Tassoni, et al.. EURO-NMD registry: federated FAIR infrastructure, innovative technologies and concepts of a patient-centred registry for rare neuromuscular disorders. Orphanet Journal of Rare Diseases, 2024, 19 (1), pp.66. ⟨10.1186/s13023-024-03059-3⟩. ⟨hal-04460667⟩
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Florent Porquet, Lin Weidong, Kévin Jehasse, Hélène Gazon, Maria Kondili, et al.. Specific DMPK-promoter targeting by CRISPRi reverses myotonic dystrophy type 1-associated defects in patient muscle cells. Molecular Therapy - Nucleic Acids, 2023, 32, pp.857 - 871. ⟨10.1016/j.omtn.2023.05.007⟩. ⟨hal-04287597⟩
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Caroline Le Guiner, T Larcher, A Lafoux, G Toumaniantz, S Webb, et al.. Characterization of the muscular and cardiac diseases of the DMSXL mouse model, a transgenic mouse model for Myotonic Dystrophy type 1. American Society of Gene & Cell Therapy, May 2023, LOS ANGELES, United States. ⟨hal-04096181⟩
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Dylan Moutachi, Mégane Lemaitre, Clément Delacroix, Onnik Agbulut, Denis Furling, et al.. Valproic acid reduces muscle susceptibility to contraction‐induced functional loss but increases weakness in two murine models of Duchenne muscular dystrophy. Clinical and Experimental Pharmacology and Physiology, In press, ⟨10.1111/1440-1681.13804⟩. ⟨hal-04146953⟩
Chiffres clés
144
Publications avec texte intégral
Open Access
53 %
Mots clés
Astrocytes
BIOLOGIE MOLECULAIRE
Myotonic Dystrophy Type 1
RNA splicing
Cytoskeleton
Gene therapy
Therapy
Dilated cardiomyopathy
Brain
ARN
Astrocyte
Mouse models
Myostatin
Exercise
Autophagy
Mouse model
Fibrosis
Myotonic Dystrophy
CTG repeats
Thérapie génique
Desmin
Maximal force
Quantitative microdialysis
Transgenic mouse
Gene Therapy
Trinucleotide Repeat Expansion
Acetylcholinesterase knockout mouse
Cultured
Hypoxia
Heart
Endurance training
Glucocorticoids
Dynamin 2
Cardiac muscle
RNA biology
Transcriptomics
Dystrophie myotonique
Diaphragm
Male
Myotonic dystrophy
DM1
RNA interference
Neuron
Muscular dystrophy
Mice
Cells
Glucocorticoid-receptor
Brain dysfunction
Centronuclear myopathy
Trinucleotide repeat expansion
Long read sequencing
Cell model
CTG repeat contractions
PacBio
Humans
DMSXL mice
Aging
Heart failure
Cell penetrating peptide
GSK3
ACETYLCHOLINESTERASE
AAV
CONGENITAL MYATHENIC SYNDROME
Dystrophie Myotonique
Antisense oligonucleotides
Transgenic mouse model
Oligodendrocytes
Duchenne muscular dystrophy
KNOCKOUT MICE
Dystrophin
CRISPRi
MBNL
Animals
Exercice
Myotonic dystrophy type 1
Myelin
CMS
Cell culture model
CRISPR/Cas9
CTG repeat instability
Oligodendrocyte
Acetylcholinesterase deficiency
Acute coronary syndrome
Expression
Myotonic dystrophy mouse models
Genotype phenotype correlation
Central nervous system
DMPK
Glutamate
PCR
Intermediate filament
Motoneuron
Gene editing
Alternative splicing
Glial cells
Myotonic Dystrophy type 1
Muscle
Skeletal muscle
Antisense oligonucleotide
GABA