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Chiral Separation, X-ray Structure, and Biological Evaluation of a Potent and Reversible Dual Binding Site AChE Inhibitor

Marco Catto , Leonardo Pisani , Eugenio de La Mora , Benny Danilo Belviso , Giuseppe Felice Mangiatordi , et al.
ACS Medicinal Chemistry Letters, 2020, 11 (5), pp.869-876. ⟨10.1021/acsmedchemlett.9b00656⟩
Journal articles hal-03014301v1
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Mechanistic Investigations of Green mEos4b Reveal a Dynamic Long-Lived Dark State

Elke de Zitter , Jacqueline Ridard , Daniel Thédié , Virgile Adam , Bernard C. Levy , et al.
Journal of the American Chemical Society, 2020, 142 (25), pp.10978-10988. ⟨10.1021/jacs.0c01880⟩
Journal articles hal-02895781v1
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Serial femtosecond crystallography on in vivo-grown crystals drives elucidation of mosquitocidal Cyt1Aa bioactivation cascade

Guillaume Tetreau , Anne-Sophie Banneville , Elena Andreeva , Aaron Brewster , Mark Hunter , et al.
Nature Communications, 2020, 11 (1), ⟨10.1038/s41467-020-14894-w⟩
Journal articles hal-02506591v1
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The C. elegans GATA transcription factor elt-2 mediates distinct transcriptional responses and opposite infection outcomes towards different Bacillus thuringiensis strains

Alejandra Zárate-Potes , Wentao Yang , Barbara Pees , Rebecca Schalkowski , Philipp Segler , et al.
PLoS Pathogens, 2020, 16 (9), pp.e1008826. ⟨10.1371/journal.ppat.1008826⟩
Journal articles hal-03014289v1
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Remote oxidative modifications induced by oxygen free radicals modify T/R allosteric equilibrium of a hyperthermophilic lactate dehydrogenase

Frédéric Halgand , Chantal Houée-Lévin , Martin Weik , Dominique Madern
Journal of Structural Biology, 2020, 210 (2), pp.107478. ⟨10.1016/j.jsb.2020.107478⟩
Journal articles hal-03011827v1
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Radiation damage and dose limits in serial synchrotron crystallography at cryo- and room temperatures

Eugenio de La Mora , Nicolas Coquelle , Charles Bury , Martin Rosenthal , James Holton , et al.
Proceedings of the National Academy of Sciences of the United States of America, 2020, 117 (8), pp.4142-4151. ⟨10.1073/pnas.1821522117⟩
Journal articles hal-03014308v1
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Dynamics of pathological aggregates and fibers

Kevin Pounot
Neurobiology. Université Grenoble Alpes [2020-..], 2020. English. ⟨NNT : 2020GRALY014⟩
Theses tel-03099901v1
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Photoswitching mechanism of a fluorescent protein revealed by time-resolved crystallography and transient absorption spectroscopy.

Joyce Woodhouse , Gabriela Nass Kovacs , Nicolas Coquelle , Lucas M. Uriarte , Virgile Adam , et al.
Nature Communications, 2020, 11 (1), pp.741. ⟨10.1038/s41467-020-14537-0⟩
Journal articles hal-02498645v1
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Development of potent reversible selective inhibitors of butyrylcholinesterase as fluorescent probes

Stane Pajk , Damijan Knez , Urban Košak , Maja Zorović , Xavier Brazzolotto , et al.
Journal of Enzyme Inhibition and Medicinal Chemistry, 2020, 35 (1), pp.498-505. ⟨10.1080/14756366.2019.1710502⟩
Journal articles hal-03014299v1