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Deposit type : Notice

Multi-target-directed ligands for treating Alzheimer's disease: Butyrylcholinesterase inhibitors displaying antioxidant and neuroprotective activities

Damijan Knez , Nicolas Coquelle , Anja Pišlar , Simon Žakelj , Marko Jukič , et al.
European Journal of Medicinal Chemistry, 2018, 156, pp.598 - 617. ⟨10.1016/j.ejmech.2018.07.033⟩
Journal articles hal-01924686v1

Structure-Based Optimization of Nonquaternary Reactivators of Acetylcholinesterase Inhibited by Organophosphorus Nerve Agents

Gianluca Santoni , J. de Sousa , Eugenio de La Mora , J. Dias , Ludovic Jean , et al.
Journal of Medicinal Chemistry, 2018, 61 (17), pp.7630-7639. ⟨10.1021/acs.jmedchem.8b00592⟩
Journal articles hal-02024531v1

The Magic of Crystal Structure-Based Inhibitor Optimization: Development of a Butyrylcholinesterase Inhibitor with Picomolar Affinity and in Vivo Activity

Urban Košak , Boris Brus , Damijan Knez , Simon Žakelj , Jurij Trontelj , et al.
Journal of Medicinal Chemistry, 2018, 61 (1), pp.119-139. ⟨10.1021/acs.jmedchem.7b01086⟩
Journal articles hal-01991973v1

Chromophore twisting in the excited state of a photoswitchable fluorescent protein captured by time-resolved serial femtosecond crystallography

Nicolas Coquelle , Michel Sliwa , Joyce Woodhouse , Giorgio Schirò , Virgile Adam , et al.
Nature Chemistry, 2018, 10 (1), pp.31-37. ⟨10.1038/nchem.2853⟩
Journal articles hal-01618533v1

Probing the Structure and Dynamics of Cells, Cell Components and Endogenous Nanoparticles Under Extreme Conditions with Neutrons

Judith Peters , Ruth Prassl , P. Oger
Biological, Physical and Technical Basics of Cell Engineering, Springer Singapore, pp.401-420, 2018
Book sections hal-02122309v1

Interaction between Insects, Toxins, and Bacteria: Have We Been Wrong So Far?

Guillaume Tetreau
Toxins, 2018, 10 (7), pp.281. ⟨10.3390/toxins10070281⟩
Journal articles hal-01989091v1

Design of tryptophan-containing mutants of the symmetrical Pizza protein for biophysical studies

Hiroki Noguchi , Bram Mylemans , Elke de Zitter , Luc van Meervelt , Jeremy R.H. Tame , et al.
Biochemical and Biophysical Research Communications, 2018, 497 (4), pp.1038-1042. ⟨10.1016/j.bbrc.2018.02.168⟩
Journal articles hal-03513224v1

Potent 3‐Hydroxy‐2‐Pyridine Aldoxime Reactivators of Organophosphate‐Inhibited Cholinesterases with Predicted Blood–Brain Barrier Penetration

Tamara Zorbaz , Anissa Braïki , Nikola Marakovic , Julien Renou , Eugenio de La Mora , et al.
Chemistry - A European Journal, 2018, 24 (38), pp.9675-9691. ⟨10.1002/chem.201801394⟩
Journal articles hal-02024542v1

Protein-assisted formation and stabilization of catalytically active polyoxometalate species

Laurens Vandebroek , Elke de Zitter , Elke De zitter , Hong Giang Thi Ly , Dragan Conić , et al.
Chemistry - A European Journal, 2018, 24 (40), pp.10099-10108. ⟨10.1002/chem.201802052⟩
Journal articles hal-03513218v1

A Long-Lived Triplet State Is the Entrance Gateway to Oxidative Photochemistry in Green Fluorescent Proteins

Martin Byrdin , Chenxi Duan , Dominique Bourgeois , Klaus Brettel
Journal of the American Chemical Society, 2018, 140 (8), pp.2897 - 2905. ⟨10.1021/jacs.7b12755⟩
Journal articles hal-01726154v1

Bacterial cell wall nanoimaging by autoblinking microscopy

Kevin Floc’h , Françoise Lacroix , Liliana Barbieri , Pascale Servant , Rémi Galland , et al.
Scientific Reports, 2018, 8 (1), ⟨10.1038/s41598-018-32335-z⟩
Journal articles hal-01930130v1

Uncharged reactivators of cholinesterases inhibited by organophosphorus nerve agents.

Nicolas Probst , Anissa Braïki , Pierre Warnault , Julien Renou , Catherine Gomez , et al.
International Meeting on Cholinesterases (13, 2018) and International Conference on Paraoxonases (7, 2018)), Sep 2018, Hradec Králové, Czech Republic
Conference poster hal-02543467v1

Increasing Polarity in Tacrine and Huprine Derivatives: Potent Anticholinesterase Agents for the Treatment of Myasthenia Gravis

Carles Galdeano , Nicolas Coquelle , Monika Cieslikiewicz-Bouet , Manuela Bartolini , Belén Pérez , et al.
Molecules, 2018, 23 (3), pp.634. ⟨10.3390/molecules23030634⟩
Journal articles hal-01807857v1

Photochemical Mechanism of an Atypical Algal Phytochrome

Uzma Choudry , Derren Heyes , Samantha Hardman , Michiyo Sakuma , Igor Sazanovich , et al.
ChemBioChem, 2018, 19 (10), pp.1036 - 1043. ⟨10.1002/cbic.201800016⟩
Journal articles hal-01807868v1

Extreme amyloid polymorphism in Staphylococcus aureus virulent PSMα peptides

Nir Salinas , Jacques-Philippe Colletier , Asher Moshe , Meytal Landau
Nature Communications, 2018, 9 (1), pp.3512. ⟨10.1038/s41467-018-05490-0⟩
Journal articles hal-01924638v1

Global spectroscopic analysis to study the regulation of the photosynthetic proton motive force: A critical reappraisal

Guillaume Allorent , Martin Byrdin , Luca Carraretto , Tomas Morosinotto , Ildikó Szabó , et al.
Biochimica biophysica acta (BBA) - Bioenergetics, 2018, 1859 (9), pp.676-683. ⟨10.1016/j.bbabio.2018.07.001⟩
Journal articles hal-02046325v1